Alkyloxyalkyliden esters of salicylic acid.



UNITED STATES Y Patented October 6, 1903.

PATENT OFFICE) JORGEN OALLSEN, OF ELBERFELD, GERMANY, ASSIGNOR TO FARBEN- FABRIKEN OF ELBERFELD (30., OF NEW YORK, N. Y., A CORPORA- TION OF NEW YORK.

ALKYLOXYALKYLIDEN ESTERS OF SALICYLIC ACID.

SPECIFICATION formingpart of Letters Patent No. 740,628, dated October 1903.

Application filed July 3, 1903. fierial No. 164,244- (lio specimens.)

To all whom it may concern:

Be it known that I, J iiEeEN OALLSEN, doctor of philosophy, chemist, residing at Elberfeld, Germany, {assignorto the FARBENFABRIKEN or ELBERFELD COMPANY, of New York, have invented a new and useful Improvement in Alkyloxyalkyliden Esters of Salicylic Acid, of which the following is a specification.

My invention relates to the production of new pharmaceutical products which are chemically alkyloxyalkyliden esters of salicylic acid having the following general formula ing either the same or two different alkyl radicals.) The new products thus produced are from'colorless to yellowish liquids soluble ClCH-O0 H I CH (See Annalen der Ohemie, Vol. 108, p. 226.)

are added little by little to sixteen parts of dry sodium salicylate while carefully cooling.

After the reaction is completed the mixture is washed with ice-water and a dilute solution of sodium carbonate in order to remove the sodium chlorid and the excess of salicylic acid contained therein, and subsequently dried over chloridof calcium.

The new ethoxyethylidensalicylate of the formulaisa yellowish oil having a faint'arom'atic odor. When treated with water, dilute acids, or alkalies, it breaks up into salicylic acid, acetaldehyde, and ethyl alcohol.

The process proceeds in an analogous manner if other alpha-halogendialkyl otherssuch as alpha-monochloroethylmethylether, alphamonochloroamylmethylether, or the like-are employed. I Of course instead of sodium salicylate other salicylates can also be used.

Having now described my invention and in what manner the'same is to be performed, what I claim as new, and desire to secure by Letters Patent, is

1. Theherein-described new alkyloxyalky- 1 nesses.

J URGEN CALLSEN.

Vitnesses:

Orro Kome,

J. A. Rrrrnnsnaus. 

